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Established the first banks in the world to save money, and was considered a major breakthrough in the world of economics and money, and here knew the meaning of the word bank is a place that kept the depositors' money, and Istrdunha in case you need them. The evolution of medicine over the years, the discovery of blood transfusions and take advantage of it. It can not be manufactured industrially blood, the scientists have to find a way to save large amounts of donated blood for use in situations of war and peace. Currently, the new type began to emerge from the banks, which began to take a new route through the discovery of the benefits of umbilical cord blood.
And when you return to the past was on the search for a donor, doctors believe the marrow bone bone marrow, which also contains stem cells producing cells of the blood and immune systems. samuel deduno But unfortunately many were dying during the long search for a donor that matches the patient's tissue type. Or due to complications resulting from the mismatch pure granted a good match; The umbilical cord blood stainless save for long periods, it is more likely to match the good and the less likely samuel deduno the events of complications because the stem cells in cord blood differ immunologically from those in the bone marrow in adults, as well as featuring as more tolerant tolerance.
- What is cord blood? After the birth of a child can directly take a small amount samuel deduno of the umbilical cord and saves in a special way in special places called cord blood banks, and this blood is not like the rest of the blood, but his specifications very special being contains a quantity of stem cells capable of rebuilding samuel deduno the blood cells and the immune system in patients samuel deduno ill Kawhitad blood leukemia and other types of cancer, where multiply blood cell composition is normal and when treated with chemotherapy to kill and rid the body of them, and the treatment of this disease should be replaced samuel deduno by places samuel deduno of industrialization in the bone marrow, which contains stem cells, producing spectacular vessels and immune, setting calls for patients to transfer marrow bone from someone who is identical to the characteristics of the patient's bone marrow, which is difficult in many cases, the umbilical cord blood was an appropriate solution for such cases, but it is more tolerant of immune complications of bone marrow transfer.
- History of the evolution of the transfer of umbilical cord blood: * noon the first evidence of the possibility of medical benefit from umbilical cord blood in 1972, and was done by giving infected with leukemia 16 years old umbilical cord blood infusion intravenous infusion. After one week found that the patient's blood contains red cells originating from stem cells of the donor. * In 1980 and began thinking samuel deduno about the comparison between the cells of the umbilical cord and bone marrow transfused, was not sure of that, but in 1989 through the clarification that umbilical cord blood contains the same amount of stem cells found in the bone marrow. * In the same year was the first transfer of stem cells from umbilical cord to the baby with a genetic disease (anemia Alvancona Fanconi anima) through samuel deduno the use of umbilical cord blood to his sister's fledgling. * In 1991, has the first process for the transfer of umbilical cord blood for a child with chronic leukemia (leukemia). Both processes have succeeded, and led to the birth of new heights in the process of transfer of umbilical samuel deduno cord blood and replace it with the process of the transfer of bone marrow. * In 1997, scientists found evidence that transplantation of umbilical cord blood - even between donor and recipient is close - is safer than bone marrow transplants.
- The objectives of the umbilical cord blood transplantation: aims transplantation of umbilical cord blood to get a source of stem cells that most closely with histological type for a particular patient. There are six genes of major Human Leukocyte Antigens or HLA (They are found on the surfaces of all cells of the body, and which recognizes the immune system cells and deal with it on the basis of being a normal cells, which belong to the same (self) and otherwise is to kill as do not belong to the same non- self. Among these genes six everyone has two copies (or alleles alleles) for each gene of genes six, each copy of them belonging to one of the parents, (there are of each Night of more than 30 different species.) and for bone marrow transplants aims doctors to matching alleles six (out of 12) most appropriate for transplantation from clinical terms., but because of the difference immune cells of umbilical samuel deduno cord blood for bone marrow cells, doctors can use samples from the umbilical cord blood match only five - or even three - of alleles HLA. deposited copies for Responsible Genetics industry for HLA proteins on chromosome No. 6. According to the rules of genetics, the probability that inherits Brothers chromosome samuel deduno No. 6 of the same father and mother, and then to be identical histologically well, is only 25%.
The differences in the immune system of the newborn leads to reduce the possibility that the immune samuel deduno cells in umbilical cord has attacked weave receiver (as weird), and thus the immune cells in umbilical cord blood is less damaging than damage samuel deduno the cells of the bone marrow. Since receiving an implant of bone marrow person does not match the type of tissue of the patient well can be fatal, if in case survived amount even if very few of immune cells leading to obtain disease graft-versus-host Graft-versus-host disease or GVHD (a phenomenon characterized by attacking the transplanted cells), and these cells are attacking the recipient's body as a stranger. This phenomenon leads to injury samuel deduno rash is accompanied by sores, in addition to liver damage, samuel deduno can develop into liver failure or severe bleeding nervous system, this disease could lead to rapid death. samuel deduno
This method is characterized by the presence of a lot of benefits that distinguish them from the process of transplanting cells from the bone marrow, which T.
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